WHAT DOES
OXBRYTA DO?

OXBRYTA INTERFERES WITH SICKLE CELL AT ITS CORE, WHICH MAY LEAD TO LESS SICKLING.

Hemoglobin Diagram

WHICH MAY LEAD TO LESS SICKLING.

Oxbryta works on hemoglobin S to interfere with the first step of the process that causes red blood cells to sickle (polymerization).

Because Oxbryta impacts this very first step, it helps to prevent sickling and hemolysis (the breakdown of red blood cells). Hemolysis can lead to anemia (having too few red blood cells).

Oxbryta helps hemoglobin do its job, that is, helping red blood cells deliver oxygen throughout the body.

Treat sickle cell at its source.

Oxbryta is the first-of-its-kind tablet that addresses sickle cell in a different way—by working directly on hemoglobin S to interfere with the process that causes red blood cells to sickle.

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